Bioactive compounds of sea cucumbers and their therapeutic effects -- Journal of Oceanology and Limnology,2016,34(3):549-558

	Cite this paper:
	SHI Shujuan, FENG Wenjing, HU Song, LIANG Shixiu, AN Nina, MAO Yongjun. Bioactive compounds of sea cucumbers and their therapeutic effects[J]. Journal of Oceanology and Limnology, 2016, 34(3): 549-558

Bioactive compounds of sea cucumbers and their therapeutic effects

SHI Shujuan, FENG Wenjing, HU Song, LIANG Shixiu, AN Nina, MAO Yongjun

Department of Geriatric Internal Medicine, Affi liated Hospital of Qingdao University, Qingdao 266003, China

Abstract:

Sea cucumbers belong to the Class Holothuroidea of marine invertebrates. They are commercially valuable and prized as a food and folk medicine in Asia. Nutritionally, sea cucumbers have an impressive profi le of valuable nutrients such as vitamins, minerals and amino acids. A number of unique biological and pharmacological activities/properties, including anticancer, anticoagulant/antithrombotic, antimicrobial, antioxidant, antihyperlipidemic, antihyperglycemic, anti-inflammatory, antihypertension and radioprotective, have been ascribed to various compounds isolated from sea cucumbers. The therapeutic properties and medicinal benefi ts of sea cucumbers can be linked to the presence of a wide array of bioactives, especially triterpene glycosides, acid mucopolysaccharide, sphingoid bases, glycolipids, fucosylated chondroitin sulfate, polysaccharides, phospholipids, cerebrosides, phosphatidylcholines, and other extracts and hydrolysates. This review highlights the valuable bioactive components as well as the multiple therapeutic properties of sea cucumbers with a view to exploring their potential uses as functional foods and a natural source of new multifunctional drugs.

Key words: sea cucumber|bioactive compounds|biological activities|pharmacological activities|therapeutic effects

Received: 2014-11-24 Revised: 2015-02-16

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Articles by SHI Shujuan

Articles by FENG Wenjing

Articles by HU Song

Articles by LIANG Shixiu

Articles by AN Nina

Articles by MAO Yongjun

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